| Solution Information | help | |
| Enzyme: | Signal transducer and activator of transcription 3 [702-738,740-752] | |
| inhibitor: | BDBM43632 | |
| substrate: | n/a | |
| Solution Type: | Aqueous | |
| pH at Preparation: | n/a | |
| Temp. Prep.: | n/a | |
| Comments: | Assay Overview: The purpose of this assay is to determine dose response curves for compounds identified as active in a previous set of experiments entitled, "Primary cell-based high throughput screening assay to measure STAT3 activation" (PubChem AID 871), and that confirmed activity in a set of experiments entitled, "Confirmation cell-based high throughput screening assay to measure STAT3 activation" (AID 1267). The compounds selected for testing in this AID met the following criteria: 1) they were declared active in AID 871 and AID 1267; 2) they were declared inactive in a set of experiments entitled, "Primary cell-based high throughput screening assay to measure STAT1 activation"(AID 932); 3) they were inactive in a set of experiments entitled, "Counterscreen assay for STAT3 activators: cell-based high throughput assay to measure NF-kappaB activation" (AID 1309); and 4) they were inactive in a set of experiments entitled, "Counterscreen assay for STAT3 activators: cell-based hig | |
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